Komen Scholar Dr. Yibin Kang aims to better understand how breast cancer cells spread to other parts of the body, particularly the bone. With Komen funding, Dr. Kang is studying a “sticky” protein called E-Selectin that is found in blood vessels and thought to promote metastasis. E-Selectin may serve as an anchor for breast cancer cells circulating through the blood vessels, enabling them to travel to the bone. Dr. Kang and team will determine if blocking E-Selectin with drugs reduces the ability of breast cancer cells to spread (metastasize).
Dr. Kang received his first major national-level grant in 2005 from Komen. This award helped launch his renowned research career, and in 2016 Dr. Kang became a Komen Scholar. For the past 12 years, Dr. Kang’s lab has been funded by Komen, including two current postdoctoral fellows.
With Dr. Kang as his mentor, Dr. Antoni Celia-Terrassa is studying how breast cancer cells change to become invasive and mobile – an important step in metastasis. Also in Dr. Kang’s lab, Dr. Minhong Shen is working to find drugs that block a protein (metadherin) that promotes metastasis, and testing these drugs as potential new treatments for metastatic breast cancer.
From the day he opened his own lab, to the days he spends training the next generation of breast cancer researchers, Dr. Kang has dedicated his life to ending this disease. In his own backyard, Dr. Kang works with the Central and South Jersey Affiliate to help educate patients and the public about breast cancer and Komen’s mission. In all he does, Dr. Kang is working tirelessly to end suffering and death from metastatic breast cancer.
Dr. Kang's Lab: https://scholar.princeton.edu/kanglab/home
- Dr. Kang loves to be outdoors. His “secret talent” is a keen sense of direction even in wilderness without GPS signal.
- He has published over 140 research articles and trained more than 60 postdoctoral fellows and students in his lab.
- Dr. Kang was born in a small fishing village in southeast China (Longhai County, Fujian Province, China )
- Dr. Celià-Terrassa is a soccer player and supporter of FC Barcelona. While earning his Ph.D., he would work late in the lab, and then run across the street to FC Barcelona stadium to attend matches.
- Dr. Shen loves dogs – especially Labrador retrievers. He had a Labrador for 12 years.
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